QIIME (canonically pronounced ‘Chime’) is a pipeline for performing microbial community analysis that integrates many third party tools which have become standard in the field. QIIME can run on a laptop, a supercomputer, and systems in between such as multicore desktops.
The quickest way to start using QIIME is with the QIIME virtual box.
Getting more information on QIIME:
Help videos: http://videos.qiime.org